MALAYSIAN JOURNAL OF CHEMISTRY (MJChem)

MJChem is double-blind peer reviewed journal published by the Malaysian Institute of Chemistry (Institut Kimia Malaysia) E-ISSN: 2550-1658

The Chemistry and Biological Activities of Secondary Metabolites from the Dipterocarpaceae Family: A Review

Agustono Wibowo
Universiti Teknologi ‬MARA Pahang Branch, Jengka Campus
Norizan Ahmat
Universiti Teknologi MARA Dengkil Campus
Mohd Fazli Mohammat
Universiti Teknologi MARA, Bandar Puncak Alam
Ahmad Sazali Hamzah
Universiti Teknologi MARA, Bandar Puncak Alam

DOI: https://doi.org/10.55373/mjchem.v27i4.30

Keywords: Dipterocarpaceae; oligostilbenoids; terpenes; flavonoid; biogenesis; bioactivity

Abstract

The Dipterocarpaceae family, one of the largest plant families, is crucial for Southeast Asia's biodiversity and holds a significant economic value due to its timber. Rich in secondary metabolites like oligostilbenoids, this family displays unique structural variations that facilitate taxonomic classification and genetic understanding. Oligostilbenoids and related compounds demonstrate diverse biological activities, such as anticancer, antimicrobial, and anti-inflammatory effects, suggesting their potential as novel therapeutic agents. This review explores the chemical diversity of secondary metabolites in the Dipterocarpaceae family, highlighting their structural diversity, biogenesis, biological properties, therapeutic potentials, and the challenges related to their bioactivity and applications. It also emphasizes the need for further research to fully understand the ecological roles and pharmacological potential of these compounds.

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Published 25 August 2025


Issue Vol 27 No 4 (2025): Malaysian Journal of Chemistry

Section