DOI: https://doi.org/10.55373/mjchem.v26i5.1

Keywords: Coriandrum sativum L; soaking; non-soaking; antioxidant; antibacterial

Abstract

Natural products offer a wide range of possibilities for the development of new remedies. Coriander (Coriandrum sativum L.) seeds have been reported to contain numerous biological activities. This study aims to determine the antioxidant and antibacterial activities of coriander seeds essential oil. The essential oil was obtained using the hydrodistillation technique from non-soaked and soaked coriander seeds. The antioxidant activity was determined using the DPPH assay, while the antibacterial activity of the essential oil was determined using the Kirby-Bauer disc diffusion method against three Gram-positive bacteria: Staphylococcus aureus (ATCC 12600), Staphylococcus epidermidis (ATCC 12228), and Bacillus cereus (ATCC 14579). The yield of essential oil for soaked coriander seeds (0.79%) was higher than that of non-soaked coriander seeds (0.54%). The DPPH assay disclosed that the essential oil obtained from non-soaked coriander seeds had inactive antioxidant activity. Furthermore, the antibacterial activity of the essential oil from soaked seeds showed a potent antibacterial effect on B. cereus and S. aureus bacteria at 14.99 mm and 14.90 mm, respectively, while the essential oil from non-soaked seeds showed a potent antibacterial effect on S. epidermidis at 8.70 mm. In conclusion, coriander seeds essential oil can be developed as a new and effective antibacterial agent by showing the inhibition zone on bacteria through these studies, which can treat infections that cause human diseases.