DOI: https://doi.org/10.55373/mjchem.v25i3.36

Keywords: Catalytic optimization; magnetic nanoparticles; supported catalyst; Suzuki-Miyaura reaction

Abstract

Supported catalysts growing a highly demand as they have the potentials to offer both the activity of molecular catalyst, and the convenience reusability of a catalyst in a different phase. The magnetic supported palladium(II)-N2O2 in the Suzuki-Miyaura C-C coupling reaction enables the facile recovery of the catalyst under optimised condition. An investigation was conducted by using 4-bromoacetophenone and phenylboronic acid as reactants with the variation of catalytic parameters, such as different of bases (NaHCO3, NaOAc, Na2CO3, K2CO3 and Et3N), catalyst loading (0.25 mmol%, 0.50 mmol% and 1.0 mmol%) and reaction temperatures (100 °C, 120 °C and 140 °C). The performances of catalytic reactions were monitored by GC-FID and the percentage conversion of product was calculated by determining the differences of initial and final peak areas. The catalyst showed an outstanding catalytic performance in the Suzuki-Miyaura C-C coupling reaction when Na2CO3 was used as a base and little catalyst usage (0.25 mmol%). The catalytic reaction was favoured at high temperature of 140 °C and longer reaction time, 24 hr. In addition, the catalyst could be separated conveniently from the reacting system with an external magnet, showed good catalytic performance even after being reused five times or more, indicating a good recyclability.