MALAYSIAN JOURNAL OF CHEMISTRY (MJChem)

MJChem is double-blind peer reviewed journal published by the Malaysian Institute of Chemistry (Institut Kimia Malaysia) E-ISSN: 2550-1658

Chemical Components and Anticholinesterase Activity of Piper ornatum N.E.Br Volatile Oil

Nik Nur Asyiqin Nik Mohammed Ainul Azman
Universiti Pendidikan Sultan Idris
Wan Mohd Nuzul Hakimi Wan Salleh
Universiti Pendidikan Sultan Idris
Nurunajah Ab Ghani
Universiti Teknologi MARA

DOI: https://doi.org/10.55373/mjchem.v24i4.209

Keywords: Piper ornatum, essential oil, acetylcholinesterase, caryophyllene oxide

Abstract

This study reports volatile oil components and anticholinesterase inhibitory activity of Piper ornatum N.E.Br (Piperaceae) essential oil collected from Malaysia. The essential oil was obtained by hydrodistillation and fully analysed by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS). Twenty-seven chemical components were identified representing 79.6% of the total oil. The essential oil contains caryophyllene oxide (31.5%), spathulenol (5.9%), aromadendrene (4.9%), and β-caryophyllene epoxide (4.5%). Anticholinesterase activity was evaluated using Ellman method. The essential oil showed significant inhibitory activity against acetylcholinesterase (I%: 70.2%) and butyrylcholinesterase (I%: 75.8%) assays.

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Published 31 December 2022


Issue Vol 24 No 4 (2022): Malaysian Journal of Chemistry

Section