Keywords: 2-thiophenecarboxaldehyde nicotinic hydrazone; 2-thiophenecarboxaldehyde benzhydrazone; 2D NMR

Abstract

Synthesis and NMR spectral studies of bidentate N and S heterocycles of 2-thiophenecarboxaldehyde nicotinic hydrazone and 2-thiophenecarboxaldehyde benzhydrazone have been carried out. The compounds, 2-thiophenecarboxaldehyde nicotinic hydrazone and 2-thiophenecarboxaldehyde benzhydrazone were synthesized by reacting stoichiometric quantities of nicotinic hydrazide and benzhydrazide with 2-thiophene carboxaldehyde in methanol in the presence of glacial acetic acid at refluxing temperature. Upon cooling the reaction mixture, the products were obtained as colorless solids. ¹H, ¹³C, ¹H-¹H COSY, and ¹H-¹³C HSQC experiments have been conducted to characterize the compounds.