FeCl3/ AgOTf Catalyzed Hydroarylation Reactions of Aryl-substituted Alkynes with Different Electron-rich Arenes
Keywords: FeCl3/AgOTf catalyst; hydroarylation; alkynes; arenes; arylalkenes
Abstract
There are many synthetic methods for the direct formation of carbon-carbon bond between arenes and alkynes. Metal-catalyzed hydroarylation reaction is one of the synthetic methods for the direct formation of new carbon-carbon bond between arenes and alkynes. The hydroarylation reaction of aryl-substituted alkynes with arenes proceeded smoothly in the presence of FeCl3/AgOTf catalyst system in a mixed solvent of trifluoroacetic acid and dichloromethane at 30ÂșC and yielded aryl-substituted alkenes in moderate to high yields. Electron rich arenes gave high yields whereas the relatively less electron rich arenes gave norminal yields.
Published 07 August 2018
Issue Vol 19 No 1 (2017): Malaysian Journal of Chemistry
Section Article