Ferulic acid ester from Jatropha podagrica (Euphorbiaceae)

  • G. C. L. Ee
Keywords: Jatropha podagrica, Euphorbiaceae, n-heptyl ferulate


A new ferulic acid ester, n-heptyl ferulate (1) together with 8-hydroxy-6,7-dimethoxycoumarin (2), acetylaleuritolic acid (3) and γ-sitosterol (4) were isolated from the stem and roots of Jatropha podagrica. Their structures were determined by using 1D and 2D NMR techniques. Compounds 2, 3 and 4 were cytotoxic towards the HeLa (cervical carcinoma) cell line with IC50 values of 39.9, 35.7 and 15.9 µg/ml respectively.