Chemical Constituents from the Roots of Malayan Murraya Koenigii (Rutaceae)

Adilah Shahidan1, Kartini Ahmad1*, Mohd Azlan Nafiah1 and Siow-Ping Tan1,2
1Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris,
35900 Tanjong Malim, Perak, Malaysia.
2Department of Physical Science, Faculty of Applied Sciences and Computing,
Tunku Abdul Rahman University College, 53300 Kuala Lumpur, Malaysia

*Corresponding author: (e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.) 



The purpose of this study is to isolate and identify alkaloid compounds from the roots of Malayan Murraya koenigii. This plant has been reported to be rich in carbazole alkaloid. The hexane and dichloromethane crude extracts (roots) were separated using thin layer and column chromatography techniques. Four carbazole alkaloids were afforded and identified as girinimbine 1, murrayafoline-A 2, mahanimbine 3 and murrayanine 4. Their structures were elucidated based on spectroscopic analysis such as UV, MS, IR, and NMR (1D; 1H, 13C, DEPT and 2D; HMQC, HMBC, COSY) and by comparison with the published data.

Key wordsMurraya koenigii; carbazole alkaloid; girinimbine; murrayafoline; mahanimbine; murrayanine; structures; spectroscopic analysis

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